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What is uncompetitive inhibition

Uncompetitive inhibition is the process of an inhibitor binding to an enzyme-substrate complex to stop the reaction of enzyme with substrate. Uncompetitive inhibitors can only bind to enzyme-substrate complexes.


Is uncompetitive inhibition reversible or irreversible?

Uncompetitive inhibition is reversible which means such an inhibitor binds reversibly to the enzyme and slows down the reaction but does not cause any covalent modification.Uncompetitive inhibitors can only bind to enzyme-substrate complexes.


What are 3 types of inhibitors?

Three types of reversible inhibitors are competitive, noncompetitive and uncompetitive inhibitors- 
In competitive inhibition, a molecule, other than the substrate, binds to the active site of the enzyme.
In non-competitive inhibition, a molecule binds to a site other than the active site of an enzyme.
Uncompetitive inhibition is the process of an inhibitor binding to an enzyme-substrate complex


Is uncompetitive inhibition allosteric?

Yes, Uncompetitive inhibition is when an inhibitor binds to an allosteric site of an enzyme, when the substrate is bound to the active site. An uncompetitive inhibitor binds only to the enzyme-substrate complex.

 

 

 

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